The Podfessors solve the case of the Teenager With Swollen Scrotum, and continue the story arc of Daniel's favorite cells, B-1 cells, and their association with protective immune responses in human Chagas disease.

Hosts: Vincent Racaniello, Dickson Despommier, and Daniel Griffin

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Links for this episode:

• B1 cells and Chagas disease (Front Immunol)
• Daniel discovers B1 cells (J Exp Med)
• Hero: Bridget Ogilvie
• Image credit
• Letters read on TWiP 166

Case Study for TWiP 166

Recent consult from gastroenterologist. 61 yo woman on trip to Thailand, Cambodia for a few weeks. Developed diarrhea, took azithromycin, 3 days. Diarrhea continued, back in states now ongoing a few weeks. Left lower abdominal pain, bloated, gassy, loose stools, stick and foul smelling. Not sexually active, but is relevant. Not restrictive in what she ate. Drank bottled water. Did not eat raw items.

Send your case diagnosis, questions and comments to twip@microbe.tv

Music by Ronald Jenkees